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In other types of OI like I, III and [url=http://www.davidhabchy.com]barbour sale[/url] IV patients survive and live their lives with few [url=http://www.1855sacramento.com/woolrich.php]woolrich bologna[/url] or maybe hundreds of fractures. OI patients [url=http://www.achbanker.com/home.php]hollister[/url] have a short life span because they have a weak respiratory system which led them to early deaths. The mildest of all types is Type I. Medicines that have done some good in the path of OI are Bisphosphonate, some of its types are easily available in Pakistan also. This drug reduces the pain and chances of fractures, though it hasn't attempted to heal the breaks completely. It happens mostly in rural areas of Pakistan due to inter family marriages, which causes severe genetic issues. More research is needed to be done on the bony disease, particularly in our country for the awareness and help of OI patients and their families.
It was said that OI is wholly genetic disease; but according to a 1964 research; about 35% of the patients born with neither of their parents carrying the effected genes. It is true that it passes through genes but not in all cases. In these cases it can happen because of complications during pregnancy, lack of collagen in bones or poor quality of collagen which make the bones break easily and frequently. In severe cases weak bones can break even by a SNEEZE!!

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